Role of Helicity on the Anticancer Mechanism of Action of Cationic-Helical Peptides
نویسندگان
چکیده
منابع مشابه
Role of Helicity on the Anticancer Mechanism of Action of Cationic-Helical Peptides
In the present study, the 26-residue amphipathic α-helical peptide A12L/A20L (Ac-KWKSFLKTFKSLKKTVLHTLLKAISS-amide) with strong anticancer activity and specificity was used as the framework to study the effects of helicity of α-helical anticancer peptides on biological activities. Helicity was systematically modulated by introducing d-amino acids to replace the original l-amino acids on the non-...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2012
ISSN: 1422-0067
DOI: 10.3390/ijms13066849